ACTIVE IMMUNIZATION OF INFANTS AGAINST DIPHTHERIA

Active Immunization against Poliomyelitis

1. A single intracutaneous inoculation with a subinfective dose of the virus of poliomyelitis produces considerable immunity. 2. Virus-serum combinations produce an appreciable immunity, providing just sufficient serum is used to protect the animal from paralysis. If there is an excess of serum, the degree of immunity is considerably reduced.

Diphtheria Immunization *

AT the beginning of the twentieth century diphtheria occupied a unique position in contrast to other infectious diseases. Its symptoms and course were well known and accurately described, the causal organism definitely recognized, and a specific remedy was available for its treatment, yet in spite of this wealth of scientific knowledge the control and prevention of the disease had proved a comp...

Oral Immunization against Diphtheria and Tetanus Infections by Fluid Dphtheria and Tetanus Toxoids

Active Immunization against Poliomyelitis in Monkeys

1. A combination of poliomyelitis virus and specific human serum is effective for the production of active immunity. 2. For each gram of active virus given intradermally as an emulsion, 6 cc. of human immune serum, injected subcutaneously, was required in our experiments to protect a monkey from paralysis. Some degree of active immunity was induced. 3. Immunity, without symptom of the disease, ...

Experiments on Active Immunization against Experimental Poliomyelitis

The results obtained in this investigation indicate that poliomyelitis virus treated with tannin, sodium ricinoleate, or formalin does not constitute a satisfactory immunizing agent in monkeys against the experimental disease.